After Nimes follow A54, after Arles N568 direction Martigues
After Martigues follow A55 direction Marseille
At the split-up to Marignane follow the A7 to Marseille (don't take Vieux Port A55)
At the split-up Marseille / Aix follow Marseille (left)
Take before-last exit: St Charles
Stay left, pass underneath the highway, after the 2nd traficlight
you got the St Charles train station on your left, go straight on
steep down, curve to the left, the hotel is on your right